Endocrine Abstracts

Introduction: Glycogen storage disease type 1a (GSD1a) is an inborn error of metabolism with several metabolic decompensations including anaerobic glycolysis and lactic acidosis but few known about GSD1a-related hypercalcemia. Here we aimed to present a putative relationship between serum Ca and the affected metabolic parameters during metabolic decompensation of GSD1a.Case report: Two patients with GSD1a and hypercalcemia were retrospectively analyzed. ...

Background: Primary hyperparathyroidism (PHPT) is associated with various musculoskeletal complaints. It is difficult to evaluate muscle strength as it is hard to extract objective data due to lack of definite methods for measurement.Objective: To assess the differences between PHPT patients and healthy controls regarding maximum foot force and plantar pressure distribution by using platform pressure measuring system [Footscan (RSscan)].<p class="abs...

Introduction: Metformin treatment was associated with decreased risk of various cancers including breast cancer. Exposure to sex steroid is related with increased risk of breast cancer. In this study, we aimed to evaluate the effect of metformin treatment on serum levels of sex steroids and sex hormone binding globulin (SHBG) in postmenopausal women with type 2 diabetes mellitus.Methods: Postmenopausal patients with newly diagnosed type 2 diabetes were r...

Background: Fahr’s disease is a rare degenerative disorder characterized by symmetrical and bilateral intracranial calcification. Movement disorders are the most common symptoms of Fahr’s disease and dystonia is an uncommon presentation which accounts for only 8% of symptomatic patients.Case report: A 47 years old female admitted to emergency department with involuntary movements of extremities and anxiety. Neurological examination was normal e...

Metabolic syndrome is an important health problem that has been shown to be associated with cardiovascular disease and mortality. Recent studies have shown the importance of inflammation in visceral fat tissue. Macrophage apoptosis inhibitor (AIM) and monocyte chemotactic protein (MCP-1) are molecules that cause migrating to visceral fat tissue of M1 macrophages that initiate adipocyte inflammation. The aim of this study is to understand the role of these molecules in the path...